Two more wins. That’s all that separates Manchester City from becoming English champions for an unprecedented fourth straight year.

The game is up, though, for Burnley, whose relegation from the Premier League was confirmed on Saturday with a game to spare after being beaten by Ange Postecoglou’s Spurs.

On a significant day at both ends of the standings, City won 4-0 at Fulham to climb above Arsenal into a two-point lead. The top two each have two games left, with Arsenal facing Manchester United on Sunday (1.30am Monday AEST).

However Arsenal finish the season, the title will be City’s if they beat both Tottenham away on Tuesday and West Ham at home on May 19.

“My players like to play with pressure. They are used to it,” said coach Pep Guardiola. “They enjoy this feeling.”

No team in the 136-year history of English soccer has won the top division for four successive years. It’s the latest record in touching distance of City, who have also reached the FA Cup final against Manchester United on May 25.

Burnley needed to beat Tottenham to stand a chance of a second straight season in the league but they lost 2-1 to join already-relegated Sheffield United in returning to the Championship.

Jacob Bruun Larsen’s 25th-minute opener ensured Burnley made a fine start in north London, but Pedro Porro equalised seven minutes later before Micky van de Ven struck Spurs’ winner in the 82nd minute.

Luton look sure to be the third team relegated after losing at West Ham 3-1 and staying three points behind Nottingham Forest, who could have sealed their fate later only to fall to a 3-2 home defeat to Chelsea.

Luton’s Albert Sambi Lokonga had looked set to spoil David Moyes’ London Stadium farewell party at West Ham when he fired the visitors into an early lead.

But second-half goals from James Ward-Prowse, Tomas Soucek and 19-year-old George Earthy gave Moyes a winning send-off in his final Hammers’ home match.

At Forest, Mykhailo Mudryk put Chelsea in front in the eighth minute, but Willy Boly soon equalised and Chelsea old boy Callum Hudson-Odoi put the home side ahead in the 74th minute.

A point would have been enough for Forest to secure safety, but two minutes after Raheem Sterling’s 80th-minute equaliser, Nicolas Jackson’s close-range header won it for Chelsea.

Everton signed off their season at Goodison Park with an uncharacteristic, jeopardy-free 1-0 victory over relegated Sheffield United, thanks to Abdoulaye Doucoure’s first goal in five months.

Sean Longstaff’s eighth goal of the season ensured Newcastle’s home campaign did not end in defeat as Brighton emerged from the long trip north with a point in a 1-1 draw.

The midfielder cancelled out Joel Veltman’s opener in first-half stoppage time to secure a point and dent the Magpies’ hopes of reeling in fifth-placed Tottenham.

Michael Olise delivered another impressive display as Crystal Palace registered their fifth win in six Premier League games by beating Wolves 3-1 at Molineux, while Yoane Wissa scored in the fifth minute of stoppage time as Brentford won 2-1 at Bournemouth.